Sanofi India Ltd
Combiflam Tablet
Combiflam Tablet is a widely used over-the-counter (OTC) painkiller and fever reducer. It is a combination medication that provides fast and effective relief for various types of mild to moderate pain and inflammation.
Active Ingredients:
Combiflam Tablet contains a fixed-dose combination of two active ingredients:
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Ibuprofen (400 mg): This is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the production of prostaglandins, which are chemicals in the body that cause pain, inflammation (swelling and redness), and fever.
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Paracetamol (Acetaminophen) (325 mg): This is an analgesic (pain reliever) and antipyretic (fever reducer). It works by acting on the temperature-regulating center in the brain to lower fever and by blocking certain pain signals in the central nervous system.
Uses:
Combiflam Tablet is used for the symptomatic relief of a wide range of conditions, including:
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Headache (including migraine)
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Toothache
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Muscular pain and body aches
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Menstrual cramps (dysmenorrhea)
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Joint pain (e.g., in arthritis)
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Fever
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Pain and inflammation associated with sprains, strains, and minor injuries
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Post-operative pain
How it Works:
The combination of ibuprofen and paracetamol provides a dual-action approach to pain and fever relief. Ibuprofen targets both pain and inflammation, while paracetamol focuses on pain and fever. This synergistic effect makes Combiflam more effective than either drug used alone for certain conditions.
Important Information and Precautions:
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Administration: It is generally recommended to take Combiflam Tablet with or after food to minimize the risk of stomach irritation.
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Dosage: The dosage should be as advised by a doctor or as indicated on the product packaging. Do not exceed the recommended dose, as overuse can lead to serious side effects. The typical adult dose is one tablet every 4 to 6 hours, not exceeding 3-4 tablets in a 24-hour period.
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Short-term Use: Combiflam is intended for short-term use (e.g., up to 3 days for fever and up to 10 days for pain). Prolonged or chronic use can increase the risk of side effects.
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Side Effects: Common side effects may include:
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Stomach upset, nausea, vomiting, or indigestion
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Dizziness or drowsiness
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Headache
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Skin rash
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Heartburn
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Serious Side Effects (with long-term or high-dose use): Stomach ulcers, gastrointestinal bleeding, kidney problems, and liver damage.
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Contraindications and Warnings: Do not take Combiflam if you have a history of:
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Allergy to ibuprofen, paracetamol, or other NSAIDs (e.g., aspirin).
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Stomach ulcers or bleeding.
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Severe liver or kidney disease.
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A recent heart attack or stroke, or are at high risk of them.
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The last trimester of pregnancy.
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Alcohol: Avoid consuming alcohol while taking this medication as it can increase the risk of liver damage and stomach bleeding.
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Interactions: Inform your doctor or pharmacist about any other medications you are taking, especially blood thinners, blood pressure medications, or other pain relievers.
Disclaimer: This information is for general knowledge and informational purposes only. It does not constitute medical advice. Always consult a healthcare professional before taking any medication.